Module Number

BIOINF4210 (entspricht BIO-4210)
Module Title

Practical Transcriptomics
Lecture Type(s)

Practical Course
ECTS 3
Work load
- Contact time
- Self study
Workload:
90 h
Class time:
30 h / 2 SWS
Self study:
60 h
Duration 1 Semester
Frequency Irregular
Language of instruction English
Type of Exam

The final grade is based on performance, a written report on each day of the practical course, and one or two short oral presentations.

Content

The focus is on the practical analysis of so-called next generation sequencing
data. Students learn the use of tools for evaluating this data. This practical
course uses real-life data; the focus is on the entire process of evaluating experimental
data, from quality analyses to in-depth statistical analyses; various
methods are compared. Topics include de-novo assembly, expression count calculation,
normalization and clustering, machine learning methods and their
application to expression data, statistical methods for calculating differential
expressions, visualization methods, and enrichment methods.

Objectives

Students will gain practical experience in designing and programming bioinformatics
software for analyzing NGS data. They will be able to use libraries
and frameworks, and will acquire knowledge or extend their knowledge of Java
or C++ and R. By working together in groups, students obtain teamwork and
collaboration skills, and they will learn about project organization and presentation
techniques. Students will know about the strengths and weaknesses
and about the limitations of various methods for evaluating high-throughput
transcriptomic data, and will be able to describe and evaluate these methods.

Allocation of credits / grading
Type of Class
Status
SWS
Credits
Type of Exam
Exam duration
Evaluation
Calculation
of Module (%)
Practical Course
P
o
3
3.0
tp, op
g
100
Prerequisite for participation BIOINF3330 Expressions Bioinformatics,

BIOINF4110 (entspricht BIO-4110) Sequence Bioinformatics,

BIOINF4120 (enstpricht BIO-4120) Bioinformatics of Structures and Systems
Lecturer / Other Nieselt
Literature

Will be provided at the beginning of the course, if necessary.

Last offered unknown
Planned for Wintersemester 2024
Assigned Study Areas BIO-PRAK, MEDZ-BIOMED